Photochemical activation of TRPA1 channels in neurons and animals

Optogenetics is a powerful research tool because it enables high-resolution optical control of neuronal activity. However, current optogenetic approaches are limited to transgenic systems expressing microbial opsins and other exogenous photoreceptors. Here, we identify optovin, a small molecule that...

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Autores principales: Kokel, David, Cheung, Chung Yan J., Mills, Robert, Coutinho-Budd, Jaeda, Huang, Liyi, Setola, Vincent, Sprague, Jared, Jin, Shan, Jin, Youngnam N., Huang, Xi-Ping, Bruni, Giancarlo, Woolf, Clifford, Roth, Bryan L., Hamblin, Michael R, Zylka, Mark J., Milan, David J., Peterson, Randall T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604056/
https://ncbi.nlm.nih.gov/pubmed/23396078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1183
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