Differential Pre-mRNA Splicing Regulates Nnat Isoforms in the Hypothalamus after Gastric Bypass Surgery in Mice

BACKGROUND: Neuronatin (NNAT) is an endoplasmic reticulum proteolipid implicated in intracellular signalling. Nnat is highly-expressed in the hypothalamus, where it is acutely regulated by nutrients and leptin. Nnat pre-mRNA is differentially spliced to create Nnat-α and -β isoforms. Genetic variati...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Scott, William R., Gelegen, Cigdem, Chandarana, Keval, Karra, Efthimia, Yousseif, Ahmed, Amouyal, Chloé, Choudhury, Agharul I., Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603916/
https://ncbi.nlm.nih.gov/pubmed/23527188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059407
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker