Critical Role for the Advanced Glycation End‐Products Receptor in Pulmonary Arterial Hypertension Etiology

BACKGROUND: Pulmonary arterial hypertension (PAH) is a vasculopathy characterized by enhanced pulmonary artery smooth muscle cell (PASMC) proliferation and suppressed apoptosis. This results in both increase in pulmonary arterial pressure and pulmonary vascular resistance. Recent studies have shown...

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Autori principali: Meloche, Jolyane, Courchesne, Antony, Barrier, Marjorie, Carter, Sophie, Bisserier, Malik, Paulin, Roxane, Lauzon‐Joset, Jean‐François, Breuils‐Bonnet, Sandra, Tremblay, Ève, Biardel, Sabrina, Racine, Christine, Courture, Christian, Bonnet, Pierre, Majka, Susan M., Deshaies, Yves, Picard, Frédéric, Provencher, Steeve, Bonnet, Sébastien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603259/
https://ncbi.nlm.nih.gov/pubmed/23525442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.005157
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