Critical Role for the Advanced Glycation End‐Products Receptor in Pulmonary Arterial Hypertension Etiology

BACKGROUND: Pulmonary arterial hypertension (PAH) is a vasculopathy characterized by enhanced pulmonary artery smooth muscle cell (PASMC) proliferation and suppressed apoptosis. This results in both increase in pulmonary arterial pressure and pulmonary vascular resistance. Recent studies have shown...

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Bibliographische Detailangaben
Hauptverfasser: Meloche, Jolyane, Courchesne, Antony, Barrier, Marjorie, Carter, Sophie, Bisserier, Malik, Paulin, Roxane, Lauzon‐Joset, Jean‐François, Breuils‐Bonnet, Sandra, Tremblay, Ève, Biardel, Sabrina, Racine, Christine, Courture, Christian, Bonnet, Pierre, Majka, Susan M., Deshaies, Yves, Picard, Frédéric, Provencher, Steeve, Bonnet, Sébastien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603259/
https://ncbi.nlm.nih.gov/pubmed/23525442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.005157
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