Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) and suppressed apoptosis. This phenotype has been associated with the upregulation of the oncoprotein survivin promoting mitochond...

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Detalhes bibliográficos
Main Authors: Courboulin, Audrey, Tremblay, Véronique L, Barrier, Marjorie, Meloche, Jolyane, Jacob, Maria Helena, Chapolard, Mathilde, Bisserier, Malik, Paulin, Roxane, Lambert, Caroline, Provencher, Steeve, Bonnet, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193170/
https://ncbi.nlm.nih.gov/pubmed/21951574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-128
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