Aldosterone Increases Early Atherosclerosis and Promotes Plaque Inflammation Through a Placental Growth Factor‐Dependent Mechanism

BACKGROUND: Aldosterone levels correlate with the incidence of myocardial infarction and mortality in cardiovascular patients. Aldosterone promotes atherosclerosis in animal models, but the mechanisms are poorly understood. METHODS AND RESULTS: Aldosterone was infused to achieve pathologically relev...

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Main Authors: McGraw, Adam P., Bagley, Jessamyn, Chen, Wei‐Sheng, Galayda, Carol, Nickerson, Heather, Armani, Andrea, Caprio, Massimiliano, Carmeliet, Peter, Jaffe, Iris Z.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603255/
https://ncbi.nlm.nih.gov/pubmed/23525413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.000018
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