Functional analysis of the human adenosine deaminase gene thymic regulatory region and its ability to generate position-independent transgene expression.
We previously observed that human ADA gene expression, required for the intrathymic maturation of T cells, is controlled by first-intron sequences. Used as a cis activator, the intron generates copy-dependent reporter expression in transgenic thymocytes, and we here dissect its critical determinants...
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| 發表在: | Mol Cell Biol |
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| Principais autores: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
1992
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1508212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.9.4170-4185.1992 |
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