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Adenoviral Insulinoma-Associated Protein 1 Promoter-Driven Suicide Gene Therapy With Enhanced Selectivity for Treatment of Neuroendocrine Cancers
BACKGROUND: Insulinoma-associated protein 1 (INSM1) is a zinc finger transcriptional repressor with a limited spatial and temporal embryonic expression pattern in neuronal and neuroendocrine tissues. Interestingly, INSM1 activity is reactivated in neuroendocrine tumors such as small-cell lung cancer...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
the Academic Division of Ochsner Clinic Foundation
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3603194/ https://ncbi.nlm.nih.gov/pubmed/23533081 |
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