Adenoviral Insulinoma-Associated Protein 1 Promoter-Driven Suicide Gene Therapy With Enhanced Selectivity for Treatment of Neuroendocrine Cancers

BACKGROUND: Insulinoma-associated protein 1 (INSM1) is a zinc finger transcriptional repressor with a limited spatial and temporal embryonic expression pattern in neuronal and neuroendocrine tissues. Interestingly, INSM1 activity is reactivated in neuroendocrine tumors such as small-cell lung cancer...

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Detalhes bibliográficos
Main Authors: Akerstrom, Victoria, Chen, Chiachen, Lan, Michael S., Breslin, Mary B.
Formato: Artigo
Idioma:Inglês
Publicado em: the Academic Division of Ochsner Clinic Foundation 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603194/
https://ncbi.nlm.nih.gov/pubmed/23533081
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