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INSM1 Promoter-Driven Adenoviral Herpes Simplex Virus Thymidine Kinase Cancer Gene Therapy for the Treatment of Primitive Neuroectodermal Tumors

The INSM1 gene encodes a developmentally regulated zinc finger transcription factor. INSM1 expression is normally absent in adult tissues, but is reactivated in neuroendocrine tumor cells. In the present study, we analyzed the therapeutic potential of an adenoviral INSM1 promoter-driven herpes simpl...

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Detalhes bibliográficos
Main Authors: Wang, Hong-Wei, Breslin, Mary B., Chen, Chiachen, Akerstrom, Victoria, Zhong, Qiu, Lan, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829462/
https://ncbi.nlm.nih.gov/pubmed/19604042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.168
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