Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals

Eitemau Tebyg

• Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia
  gan: Wang, Jinyong, et al.
  Cyhoeddwyd: (2010)
• Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis
  gan: Wang, Jinyong, et al.
  Cyhoeddwyd: (2011)
• Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis
  gan: Chang, Yuan-I, et al.
  Cyhoeddwyd: (2015)
• Notch1 Gene Mutations Target KRAS G12D-expressing CD8(+) Cells and Contribute to Their Leukemogenic Transformation
  gan: Kong, Guangyao, et al.
  Cyhoeddwyd: (2013)
• Notch1 gene mutations target KRAS G12D-expressing CD8(+) cells and contribute to their leukemogenic transformation.
  gan: Kong, Guangyao, et al.
  Cyhoeddwyd: (2013)