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Epileptiform stimulus increases Homer 1a expression to modulate synapse number and activity in hippocampal cultures
Neurons adapt to seizure activity structurally and functionally to attenuate hyperactive neural circuits. Homer proteins provide a scaffold in the postsynaptic density (PSD) by binding to ligands through an EVH1 domain and to other Homer proteins by a coiled-coil domain. The short Homer isoform 1a (...
में बचाया:
| मुख्य लेखकों: | , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Physiological Society
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602934/ https://ncbi.nlm.nih.gov/pubmed/23274309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00580.2012 |
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