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Motif analysis in DNAse hypersensitivity regions uncovers distal cis elements associated with gene expression

Reliable identification of cis regulatory elements influencing transcription remains a challenging problem in molecular bioinformatics. This is especially true for enhancer elements which are often located hundreds of kilobases from the gene promoter. High resolution DNase hypersensitivity and conne...

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Bibliografiske detaljer
Main Authors: Ziemann, Mark, Kaspi, Antony, Lazarus, Ross, El-Osta, Assam
Format: Artigo
Sprog:Inglês
Udgivet: Biomedical Informatics 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602893/
https://ncbi.nlm.nih.gov/pubmed/23519433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009212
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