Kruppel-like factor 2 protects against ischemic stroke by regulating endothelial blood brain barrier function

During an ischemic stroke normal brain endothelial function is perturbed, resulting in blood brain barrier (BBB) breakdown with subsequent infiltration of activated inflammatory blood cells, ultimately leading to neuronal cell death. Kruppel-like factor 2 (KLF2) is regulated by flow, is highly expre...

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Hlavní autoři: Shi, Hong, Sheng, Baiyang, Zhang, Feng, Wu, Chunying, Zhang, Rongli, Zhu, Junqing, Xu, Kui, Kuang, Youzhi, Jameson, Stephen C., Lin, Zhiyong, Wang, Yanming, Chen, Jun, Jain, Mukesh K., Atkins, G. Brandon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602774/
https://ncbi.nlm.nih.gov/pubmed/23335794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00712.2012
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