Kruppel-like factor 2 protects against ischemic stroke by regulating endothelial blood brain barrier function

During an ischemic stroke normal brain endothelial function is perturbed, resulting in blood brain barrier (BBB) breakdown with subsequent infiltration of activated inflammatory blood cells, ultimately leading to neuronal cell death. Kruppel-like factor 2 (KLF2) is regulated by flow, is highly expre...

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Detalhes bibliográficos
Main Authors: Shi, Hong, Sheng, Baiyang, Zhang, Feng, Wu, Chunying, Zhang, Rongli, Zhu, Junqing, Xu, Kui, Kuang, Youzhi, Jameson, Stephen C., Lin, Zhiyong, Wang, Yanming, Chen, Jun, Jain, Mukesh K., Atkins, G. Brandon
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602774/
https://ncbi.nlm.nih.gov/pubmed/23335794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00712.2012
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