Endothelial Krüppel-Like Factor 4 Modulates Pulmonary Arterial Hypertension

Krüppel-like factor 4 (KLF4) is a transcription factor expressed in the vascular endothelium, where it promotes anti-inflammatory and anticoagulant states, and increases endothelial nitric oxide synthase expression. We examined the role of endothelial KLF4 in pulmonary arterial (PA) hypertension (PA...

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Hlavní autoři: Shatat, Mohammad A., Tian, Hongmei, Zhang, Rongli, Tandon, Gaurav, Hale, Andrew, Fritz, Jason S., Zhou, Guangjin, Martínez-González, José, Rodríguez, Cristina, Champion, Hunter C., Jain, Mukesh K., Hamik, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2014
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068930/
https://ncbi.nlm.nih.gov/pubmed/24156273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0135OC
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