Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors

Hemoglobin subunit alpha (HBA) expression in endothelial cells (ECs) has recently been shown to control vascular tone and function. We sought to elucidate the transcriptional regulation of HBA expression in the EC. Gain of KLF2 or KLF4 function studies led to significant induction of HBA in ECs. An...

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發表在:Vasc Med
Main Authors: Sangwung, Panjamaporn, Zhou, Guangjin, Lu, Yuan, Liao, Xudong, Wang, Benlian, Mutchler, Stephanie M, Miller, Megan, Chance, Mark R, Straub, Adam C, Jain, Mukesh K
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898218/
https://ncbi.nlm.nih.gov/pubmed/28825355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1358863X17722211
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