Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors

Hemoglobin subunit alpha (HBA) expression in endothelial cells (ECs) has recently been shown to control vascular tone and function. We sought to elucidate the transcriptional regulation of HBA expression in the EC. Gain of KLF2 or KLF4 function studies led to significant induction of HBA in ECs. An...

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Gepubliceerd in:Vasc Med
Hoofdauteurs: Sangwung, Panjamaporn, Zhou, Guangjin, Lu, Yuan, Liao, Xudong, Wang, Benlian, Mutchler, Stephanie M, Miller, Megan, Chance, Mark R, Straub, Adam C, Jain, Mukesh K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898218/
https://ncbi.nlm.nih.gov/pubmed/28825355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1358863X17722211
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