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Alterations in Prefrontal-Limbic Functional Activation and Connectivity in Chronic Stress-Induced Visceral Hyperalgesia

Repeated water avoidance stress (WAS) induces sustained visceral hyperalgesia (VH) in rats measured as enhanced visceromotor response to colorectal distension (CRD). This model incorporates two characteristic features of human irritable bowel syndrome (IBS), VH and a prominent role of stress in the...

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Détails bibliographiques
Auteurs principaux: Wang, Zhuo, Ocampo, Marco A., Pang, Raina D., Bota, Mihail, Bradesi, Sylvie, Mayer, Emeran A., Holschneider, Daniel P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602545/
https://ncbi.nlm.nih.gov/pubmed/23527114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059138
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