Alterations in Prefrontal-Limbic Functional Activation and Connectivity in Chronic Stress-Induced Visceral Hyperalgesia

Repeated water avoidance stress (WAS) induces sustained visceral hyperalgesia (VH) in rats measured as enhanced visceromotor response to colorectal distension (CRD). This model incorporates two characteristic features of human irritable bowel syndrome (IBS), VH and a prominent role of stress in the...

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Autores principales: Wang, Zhuo, Ocampo, Marco A., Pang, Raina D., Bota, Mihail, Bradesi, Sylvie, Mayer, Emeran A., Holschneider, Daniel P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602545/
https://ncbi.nlm.nih.gov/pubmed/23527114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059138
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