Heme status affects human hepatic messenger RNA and microRNA expression

AIM: To assess effects of heme on messenger RNA (mRNA) and microRNA (miRNA) profiles of liver cells derived from humans. METHODS: We exposed human hepatoma cell line Huh-7 cells to excess iron protoporphyrin (heme) (10 μmol/L) or induced heme deficiency by addition of 4, 6-dioxoheptanoic acid (500 μ...

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Detalhes bibliográficos
Main Authors: Bonkovsky, Herbert L, Hou, Weihong, Steuerwald, Nury, Tian, Qing, Li, Ting, Parsons, Judy, Hamilton, Alicia, Hwang, Sunil, Schrum, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2013
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Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602476/
https://ncbi.nlm.nih.gov/pubmed/23538684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v19.i10.1593
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