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MicroRNA-196 Represses Bach1 Protein and HCV Gene Expression in Human Hepatoma Cells Expressing Hepatitis C Viral Proteins

Hepatitis C virus (HCV) directly induces oxidative stress and liver injury. Bach1, a zipper (bZip) mammalian transcriptional repressor, negatively regulates heme oxygenase 1 (HMOX1), a key cytoprotective enzyme that has anti-oxidant and anti-inflammatory activities. microRNAs are small non-coding RN...

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Bibliografiske detaljer
Main Authors: Hou, Weihong, Tian, Qing, Zheng, Jianyu, Bonkovsky, Herbert L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862129/
https://ncbi.nlm.nih.gov/pubmed/20127796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23401
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