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MicroRNA-196 Represses Bach1 Protein and HCV Gene Expression in Human Hepatoma Cells Expressing Hepatitis C Viral Proteins
Hepatitis C virus (HCV) directly induces oxidative stress and liver injury. Bach1, a zipper (bZip) mammalian transcriptional repressor, negatively regulates heme oxygenase 1 (HMOX1), a key cytoprotective enzyme that has anti-oxidant and anti-inflammatory activities. microRNAs are small non-coding RN...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862129/ https://ncbi.nlm.nih.gov/pubmed/20127796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23401 |
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