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The let-7 microRNA Enhances Heme Oxygenase-1 by Suppressing Bach1 and Attenuates Oxidant Injury in Human Hepatocytes

The let-7 microRNA (miRNA) plays important roles in human liver development and disease such as hepatocellular carcinoma, liver fibrosis and hepatitis wherein oxidative stress accelerates the progression of these diseases. To date, the role of the let-7 miRNA family in modulation of heme oxygenase 1...

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Detalhes bibliográficos
Main Authors: Hou, Weihong, Tian, Qing, Steuerwald, Nury M., Schrum, Laura W., Bonkovsky, Herbert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480558/
https://ncbi.nlm.nih.gov/pubmed/22698995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.06.001
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