Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma

Human papillomavirus-associated head and neck squamous cell carcinomas (HPV-HNSCC) originate in the tonsils, the major lymphoid organ that orchestrates immunity to oral infections. Despite its location, the virus escapes immune elimination during malignant transformation and progression. Here, we pr...

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Detalhes bibliográficos
Main Authors: Lyford-Pike, Sofia, Peng, Shiwen, Young, Geoffrey D., Taube, Janis M., Westra, William H., Akpeng, Belinda, Bruno, Tullia C., Richmon, Jeremy D., Wang, Hao, Bishop, Justin A., Chen, Lieping, Drake, Charles G., Topalian, Suzanne L., Pardoll, Drew M., Pai, Sara I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602406/
https://ncbi.nlm.nih.gov/pubmed/23288508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2384
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