Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine

Although therapeutic HPV vaccines are able to elicit systemic HPV-specific immunity, clinical responses have not always correlated with levels of vaccine-induced CD8(+) T cells in human clinical trials. This observed discrepancy may be attributable to an immunosuppressive tumor microenvironment in w...

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Hlavní autoři: Peng, Shiwen, Lyford-Pike, Sofia, Akpeng, Belinda, Wu, Annie, Hung, Chien-Fu, Hannaman, Drew, Saunders, John R., Wu, T.-C., Pai, Sara I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2012
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543472/
https://ncbi.nlm.nih.gov/pubmed/23011589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1322-5
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