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Non-canonical NF-κB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions

RelB and NF-κB2 are the main effectors of NF-κB non-canonical signaling and play critical roles in many physiological processes. However, their role in hematopoietic stem/progenitor cell (HSPC) maintenance has not been characterized. To investigate this, we generated RelB/NF-κB2 double-knockout (dKO...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhao, Chen, Xiu, Yan, Ashton, John, Xing, Lianping, Morita, Yoshikazu, Jordan, Craig T., Boyce, Brendan F.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602314/
https://ncbi.nlm.nih.gov/pubmed/22290873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1050
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