A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans

Although a cure for HCV is on the near horizon, emerging drug cocktails will be expensive, associated with side-effects and resistance making a global vaccine an urgent priority given the estimated high incidence of infection around the world. Due to the highly heterogeneous nature of HCV, an effect...

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Main Authors: Law, John Lok Man, Chen, Chao, Wong, Jason, Hockman, Darren, Santer, Deanna M., Frey, Sharon E., Belshe, Robert B., Wakita, Takaji, Bukh, Jens, Jones, Christopher T., Rice, Charles M., Abrignani, Sergio, Tyrrell, D. Lorne, Houghton, Michael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602185/
https://ncbi.nlm.nih.gov/pubmed/23527266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059776
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