A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans

Although a cure for HCV is on the near horizon, emerging drug cocktails will be expensive, associated with side-effects and resistance making a global vaccine an urgent priority given the estimated high incidence of infection around the world. Due to the highly heterogeneous nature of HCV, an effect...

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Main Authors: Law, John Lok Man, Chen, Chao, Wong, Jason, Hockman, Darren, Santer, Deanna M., Frey, Sharon E., Belshe, Robert B., Wakita, Takaji, Bukh, Jens, Jones, Christopher T., Rice, Charles M., Abrignani, Sergio, Tyrrell, D. Lorne, Houghton, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602185/
https://ncbi.nlm.nih.gov/pubmed/23527266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059776
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