Airway epithelial cells initiate the allergen response through transglutaminase 2 by inducing IL-33 expression and a subsequent Th2 response

BACKGROUND: Transglutaminase 2 (TG2) is a post-translational protein-modifying enzyme that catalyzes the transamidation reaction, producing crosslinked or polyaminated proteins. Increased TG2 expression and activity have been reported in various inflammatory conditions, such as rheumatoid arthritis,...

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Hlavní autoři: Oh, Keunhee, Seo, Myung Won, Lee, Ga Young, Byoun, Ok-Jin, Kang, Hye-Ryun, Cho, Sang-Heon, Lee, Dong-Sup
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602182/
https://ncbi.nlm.nih.gov/pubmed/23496815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-35
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