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Intratracheal myriocin enhances allergen‐induced Th2 inflammation and airway hyper‐responsiveness
INTRODUCTION: Ceramide is the central substrate of sphingolipid metabolism and plays a key role in cellular signal transduction pathways, regulating apoptosis, differentiation, and chemotaxis. Alterations in airway ceramide levels are observed in multiple pulmonary diseases and recent human genetic...
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Pubblicato in: | Immun Inflamm Dis |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
John Wiley and Sons Inc.
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893390/ https://ncbi.nlm.nih.gov/pubmed/27621809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.110 |
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