Intratracheal myriocin enhances allergen‐induced Th2 inflammation and airway hyper‐responsiveness

INTRODUCTION: Ceramide is the central substrate of sphingolipid metabolism and plays a key role in cellular signal transduction pathways, regulating apoptosis, differentiation, and chemotaxis. Alterations in airway ceramide levels are observed in multiple pulmonary diseases and recent human genetic...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Edukulla, Ramakrishna, Rehn, Kira Lee, Liu, Bo, McAlees, Jaclyn W., Hershey, Gurjit K., Wang, Yui Hsi, Lewkowich, Ian, Lindsley, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893390/
https://ncbi.nlm.nih.gov/pubmed/27621809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.110
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