Expression, Characterization and Inhibition of Toxoplasma gondii 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase

The apicomplexan parasite Toxoplasma gondii, the causative agent of toxoplasmosis, is an important human pathogen. 1-Deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) in the non-mevalonate isoprene biosynthesis pathway is essential to the organism and therefore a target for developing anti-toxopla...

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Autores principales: Cai, Guobin, Deng, Lisheng, Xue, Jian, Moreno, Silvia N.J., Striepen, Boris, Song, Yongcheng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602143/
https://ncbi.nlm.nih.gov/pubmed/23428849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.01.097
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