Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica

Aquaporin-4 (AQP4) is a water-selective transporter expressed in astrocytes throughout the central nervous system, as well as in kidney, lung, stomach and skeletal muscle. The two AQP4 isoforms produced by alternative spicing, M1 and M23 AQP4, form heterotetramers that assemble in cell plasma membra...

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Bibliographic Details
Main Authors: Verkman, Alan S, Ratelade, Julien, Rossi, Andrea, Zhang, Hua, Tradtrantip, Lukmanee
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601948/
https://ncbi.nlm.nih.gov/pubmed/21552296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.27
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