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The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation.

Expression of the human osteocalcin promoter is negatively regulated by glucocorticoids in vivo. In vitro DNase I and exonuclease III footprinting analysis showed binding of purified glucocorticoid receptor in close proximity to and overlapping with the TATA box of the osteocalcin gene. These result...

詳細記述

保存先:
書誌詳細
主要な著者: Strömstedt, P E, Poellinger, L, Gustafsson, J A, Carlstedt-Duke, J
フォーマット: Artigo
言語:Inglês
出版事項: 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC360193/
https://ncbi.nlm.nih.gov/pubmed/2038339
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