Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

Activated glucocorticoid receptor protein, purified to 40-60% homogeneity from rat liver extracts, binds selectively in vitro to a cloned fragment of murine mammary tumor virus (MTV) DNA. The DNA fragment tested contains about half of the sequences present in intact MTV DNA, and its rate of transcri...

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Main Authors: Payvar, F, Wrange, O, Carlstedt-Duke, J, Okret, S, Gustafsson, J A, Yamamoto, K R
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC349102/
https://ncbi.nlm.nih.gov/pubmed/6273877
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