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Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

Activated glucocorticoid receptor protein, purified to 40-60% homogeneity from rat liver extracts, binds selectively in vitro to a cloned fragment of murine mammary tumor virus (MTV) DNA. The DNA fragment tested contains about half of the sequences present in intact MTV DNA, and its rate of transcri...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Payvar, F, Wrange, O, Carlstedt-Duke, J, Okret, S, Gustafsson, J A, Yamamoto, K R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1981
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273877/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.6628
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