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Hysteresis as a Marker for Complex, Overlapping Landscapes in Proteins
Topologically complex proteins fold by multiple routes as a result of hard-to-fold regions of the proteins. Oftentimes these regions are introduced into the protein scaffold for function and increase frustration in the otherwise smooth-funneled landscape. Interestingly, while functional regions add...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601837/ https://ncbi.nlm.nih.gov/pubmed/23525263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz301893w |
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