EpCAM proteolysis: new fragments with distinct functions?

EpCAM [epithelial cell adhesion molecule; CD326 (cluster of differentiation 326)] is highly expressed on epithelium-derived tumours and can play a role in cell proliferation. Recently, RIP (regulated intramembrane proteolysis) has been implicated as the trigger for EpCAM-mediated proliferative signa...

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Bibliographic Details
Main Authors: Schnell, Ulrike, Kuipers, Jeroen, Giepmans, Ben N. G.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2013
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601740/
https://ncbi.nlm.nih.gov/pubmed/23409978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20120128
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