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Regioselective Opening of myo-Inositol Orthoesters: Mechanism and Synthetic Utility

[Image: see text] Acid hydrolysis of myo-inositol 1,3,5-orthoesters, apart from orthoformates, exclusively affords the corresponding 2-O-acyl myo-inositol products via a 1,2-bridged five-membered ring dioxolanylium ion intermediate observed by NMR spectroscopy. These C-2-substituted inositol derivat...

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Main Authors: Godage, Himali Y., Riley, Andrew M., Woodman, Timothy J., Thomas, Mark P., Mahon, Mary F., Potter, Barry V. L.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2013
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601604/
https://ncbi.nlm.nih.gov/pubmed/23438216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo3027774
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