Accelerated Sinus Rhythm Prevents Catecholaminergic Polymorphic Ventricular Tachycardia in Mice and in Patients

RATIONALE: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is caused by mutations in cardiac ryanodine receptor (RyR2) or calsequestrin (Casq2) genes. Sinoatrial node dysfunction associated with CPVT may increase the risk for ventricular arrhythmia. OBJECTIVE: To test the hypothesis tha...

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Main Authors: Faggioni, Michela, Hwang, Hyun Seok, van der Werf, Christian, Nederend, Ineke, Kannankeril, Prince J., Wilde, Arthur A.M., Knollmann, Björn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601570/
https://ncbi.nlm.nih.gov/pubmed/23295832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.300076
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