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Accelerated Sinus Rhythm Prevents Catecholaminergic Polymorphic Ventricular Tachycardia in Mice and in Patients

RATIONALE: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is caused by mutations in cardiac ryanodine receptor (RyR2) or calsequestrin (Casq2) genes. Sinoatrial node dysfunction associated with CPVT may increase the risk for ventricular arrhythmia. OBJECTIVE: To test the hypothesis tha...

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書誌詳細
主要な著者: Faggioni, Michela, Hwang, Hyun Seok, van der Werf, Christian, Nederend, Ineke, Kannankeril, Prince J., Wilde, Arthur A.M., Knollmann, Björn C.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601570/
https://ncbi.nlm.nih.gov/pubmed/23295832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.300076
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