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The CB(2)-preferring agonist JWH015 also potently and efficaciously activates CB(1) in autaptic hippocampal neurons
The G protein coupled receptors CB(1) and CB(2) are targets for the psychoactive constituents of cannabis, chief among them Δ(9)-THC. They are also key components of the multifunctional endogenous cannabinoid signaling system. CB(1) and CB(2) receptors modulate a wide variety of physiological system...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601544/ https://ncbi.nlm.nih.gov/pubmed/22921769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2012.08.002 |
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