The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae.

The immunosuppressants cyclosporin A, FK506, and rapamycin inhibit growth of unicellular eukaryotic microorganisms and also block activation of T lymphocytes from multicellular eukaryotes. In vitro, these compounds bind and inhibit two different types of peptidyl-prolyl cis-trans isomerases. Cyclosp...

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Détails bibliographiques
Auteurs principaux: Heitman, J, Koller, A, Kunz, J, Henriquez, R, Schmidt, A, Movva, N R, Hall, M N
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC360149/
https://ncbi.nlm.nih.gov/pubmed/7687745
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