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Structural engineering of pMHC reagents for T Cell vaccines and diagnostics
MHC class I peptide complexes (pMHC) are routinely used to enumerate T cell populations, and are currently being evaluated as vaccines to tumors and specific pathogens. Herein we describe the structures of three generations of single-chain pMHC progressively designed for the optimal presentation of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601489/ https://ncbi.nlm.nih.gov/pubmed/17719490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.07.010 |
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