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Rac1 Controls Schwann Cell Myelination through cAMP and NF2/merlin

During peripheral nervous system development, Schwann cells (SCs) surrounding single large axons differentiate into myelinating SCs. Previous studies implicate RhoGTPases in SC myelination, but the mechanisms involved in RhoGTPase regulation of SC myelination are unknown. Here, we show that SC myeli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Li, Moon, Chandra, Niehaus, Karen, Zheng, Yi, Ratner, Nancy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601465/
https://ncbi.nlm.nih.gov/pubmed/23197717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2461-12.2012
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