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Cdc42 Regulates Schwann Cell Radial Sorting and Myelin Sheath Folding Through NF2/Merlin-Dependent and Independent Signaling

The Rho family GTPase Cdc42 has been implicated in developmental Schwann cell (SC) proliferation, providing sufficient SCs for radial sorting of axons preceding SC differentiation in the peripheral nervous system. We generated Cdc42 conditional knockout (Cdc42-CKO) mice and confirmed aberrant axon s...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Guo, Li, Moon, Chandra, Zheng, Yi, Ratner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447142/
https://ncbi.nlm.nih.gov/pubmed/24014231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22567
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