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Expression of functionally active sialylated human erythropoietin in plants
Recombinant human erythropoietin (rhEPO), a glycohormone, is one of the leading biopharmaceutical products. The production of rhEPO is currently restricted to mammalian cell expression systems because of rhEPO's highly complex glycosylation pattern, which is a major determinant for drug-efficac...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY-VCH Verlag
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601435/ https://ncbi.nlm.nih.gov/pubmed/23325672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201200363 |
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