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A High-Throughput, Flow Cytometry-Based Method to Quantify DNA-End Resection in Mammalian Cells

Replication protein A (RPA) is an essential trimeric protein complex that binds to single-stranded DNA (ssDNA) in eukaryotic cells and is involved in various aspects of cellular DNA metabolism, including replication and repair. Although RPA is ubiquitously expressed throughout the cell cycle, it loc...

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Détails bibliographiques
Auteurs principaux: Forment, Josep V, Walker, Rachael V, Jackson, Stephen P
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601416/
https://ncbi.nlm.nih.gov/pubmed/22893507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.22155
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