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The interaction between murine melanoma and the immune system reveals that prolonged responses predispose for autoimmunity

An assessment of antitumor immunity versus autoimmunity as provoked by the specific depletion of Foxp3(+) Tregs is now possible with the development of Foxp3-diphtheria toxin receptor-like transgenic mouse models. We have used the poorly immunogenic B16F10 melanoma model to characterize a very heter...

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Autori principali: Ngiow, Shin Foong, von Scheidt, Bianca, Möller, Andreas, Smyth, Mark J., Teng, Michele W. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601172/
https://ncbi.nlm.nih.gov/pubmed/23524369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23036
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