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Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer
The blockade of the PD-1 pathway can increase the production of interferon γ by tumor-specific T cells located within or in the proximity of the malignant lesion, thereby increasing the chemokine-dependent trafficking of immune effector cells. This can boost the efficacy of adoptive T-cell therapy t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601154/ https://ncbi.nlm.nih.gov/pubmed/23524510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22691 |
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