IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques

Intramuscular injection of macaques with an IL-12 expression plasmid (0.1 or 0.4 mg DNA/animal) optimized for high level of expression and delivered using in vivo electroporation, resulted in the detection of systemic IL-12 cytokine in the plasma. Peak levels obtained by day 4–5 post injection were...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Jalah, Rashmi, Patel, Vainav, Kulkarni, Viraj, Rosati, Margherita, Alicea, Candido, Ganneru, Brunda, von Gegerfelt, Agneta, Huang, Wensheng, Guan, Yongjun, Broderick, Kate E., Sardesai, Niranjan Y., LaBranche, Celia, Montefiori, David C., Pavlakis, George N., Felber, Barbara K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2012
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601136/
https://ncbi.nlm.nih.gov/pubmed/22894956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.21407
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla