Serum factors can modulate the developmental clock of gamma- to beta-globin gene switching in somatic cell hybrids.

The fusion of human fetal erythroid (HFE) cells with mouse erythroleukemia (MEL) cells produces stable synkaryons (HFE x MEL) which can be monitored for extended periods of time in culture. Initially these hybrids express a human fetal globin program (gamma >> beta), but after weeks or months in cul...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Zitnik, G, Li, Q, Stamatoyannopoulos, G, Papayannopoulou, T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4844-4851.1993
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